This lecture will introduce the twelve-official physiology to the practitioner of Chinese medicine, as conveyed by Chapter Eight of the Suwen, “The Secret Compendium of the Miraculous Orchid.” It will provide an overview of the opening passages to that chapter looking at the original Chinese text and English translation. It will then delve into the etymology of selected lines, providing the student of Classical Chinese medicine with a window into the holotropic landscape of early Chinese medical writings. We will explore the ways in which these insights illuminate the human body, health, and disease as dynamic, cybernetic systems. The presentation will include case studies to illustrate the use of twelve-official physiology to inform treatment planning, including the selection of herbal formulas, acupuncture points, and lifestyle guidance.