Western science and medicine is just now recognizing the importance of the microbiome, though its existence and function has been known for thousands of years in Chinese medicine and Ayurveda. Changes to our bodies and minds from climactic influences to circadian rhythms, many via the microbiome, are baselines of assessment and suggest lifestyle guidance in Chinese medicine and Ayurveda. The triple warmer, mo yuan, spleen qi, accumulation of dampness or toxins, quality of the shen, and influence of lifestyle and dietary choices are all directly related to the microbiome. Shea will explain how the many influences affect the microbiome and its relationships to key concepts in both Ayurveda and Chinese medicine–especially as we enter cold and flu season.